Showing posts with label lung cancer. Show all posts
Showing posts with label lung cancer. Show all posts

Saturday, September 3, 2011

Traditional Versus Minimally Invasive Lung Cancer Surgery


There are a number of reasons, the operation is performed on pluća.Najčešći reason including cancer. If a mass is identified in lung tissue, the surgical team will be assigned to remove it. There are several approaches that can be taken, depending on where a mass, as well as its size. Surgery can also perform the fix, or collapsed lung to drain fluid that accumulates in the vicinity.

Today, minimally invasive techniques are used to reduce the likelihood of complications and provide a shorter recovery period for the patient. In this article, we will provide an overview of the differences between traditional thoracotomy and minimally invasive surgery of lung cancer. While the former is still done in some circumstances, the latter is becoming increasingly common.

The types of surgical procedures

First, it is worth considering the different operations performed on the lungs. As noted, most surgical procedures are done to cure lung cancer (LC). If this mass is small and can be found only in a small piece of tissue, a wedge resection is performed to remove that part.

In cases where cancer cells are detected within a larger piece of tissue, lobectomy can be done. This is a procedure in which an entire lobe is removed. If you need to remove two adjacent lobes, the procedure is called bilobectomy.

Friday, September 2, 2011

Stop! Read This Before Making Any Decision Regarding Lung Cancer


Are you worried about the tips and advice in relation to lung cancer or similar facts in some way related to lung cancer? If so, under the piece provides you with useful insights that will simply not be aware of. Take time to read through it and know that you will not be disappointed when you're done.

Thoracotomy is the initial step in the treatment of lung cancer. This is what open your chest for surgery was a surgical procedure to be implemented there. When lung cancer, you are likely to undergo surgical resekcije.Liječnik would only approve it if the specific disease has not spread beyond the lungs.

Thoracotomy is the first step in treating lung cancer with surgical resection, the second step is a median sternotomy. This refers to cutting through the breastbone to the heart or lungs. Of course, since they are suffering from lung cancer, you know where the doctor is at the forefront.













Monday, August 29, 2011

Origin of Connective Tissue Type Mesotheliomas from Multipotential Spindle Cells



Another interesting study entitled "Pleural mesothelioma of connective tissue type, localized fibrous tumor of the pleura, and reactive hyperplasia submesothelial immunohistochemical comparison." Moutaiz by Al-Izzi, Nicola P. Thurlow, Professor Bryan Corrin -. Journal of Pathology, Volume 158, Issue 1, pages 41-44, May 1989 Here is an excerpt: "Abstract - Ten diffuse pleural mesotheliomas connective tissue type were compared with 14 examples of pleural granulation tissue and 7 localized fibrous tumors of the pleura, using immunohistochemistry to identify cytokeralins oflow and high molecular weight and vimentin. low-molecular-weight cytokeratin and vimentin are both delected in 8 of 10 mesotheliomas and 12 of 14 reactive iesions. cylokeratin high molecular weight is rarely detected or lesions. seven of localized fibrous tumors of the pleura are all positive and negative for virnentin for cytokeratins. These results support the origin of connective tissue type mesotheliomas multipotential submesothelial spindle cells and localized fibrous tumors of the pleura from any conventional fibroblasts or resting submesothelial stem cells. cytokeratin antibodies to help distinguish these two neoplasms, but does not provide help in difficult diagnostic problem of distinguishing mesotheliomas of the connective tissue type of pleural reaction is characterized by abundant granulation tissue ."

Another interesting study titled, "Final analysis of multi-center, double-blind, placebo-controlled, randomized phase II trial of gemcitabine / cisplatin (GC) plus bevacizumab (B) or placebo (P) in patients (pts ) with malignant mesothelioma (MM) "-

Another interesting study titled, "Final analysis of multi-center, double-blind, placebo-controlled, randomized phase II trial of gemcitabine / cisplatin (GC) plus bevacizumab (B) or placebo (P) in patients (pts ) with malignant mesothelioma (MM) "-














Saturday, August 27, 2011

Symptoms, Diagnosis And Treatment Of Epithelioid Mesothelioma


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Mesothelioma is a serious disease of cancer with low survival rates despite a variety of new treatment options that have helped to increase longevity. Statistics show that the average survival time after diagnosis is about one dana.Razdoblje can increase up to two years if the treatment is carried out aggressively. It was found that more than 95% of cases, mesothelioma is caused by exposure to asbestos.

Most people were previously aware of the dangers caused by exposure to asbestos as mesothelioma occurs after about 20-40 years after asbestos exposure. For this reason, this disease is also referred to as 'old people's disease', as people in 60 or 70 usually contract the disease. The higher forecast to help patients take better treatment, and in turn a better age.

epithelium is a tissue separating the different regions of the body. As in the case of epithelial cells in the skin are separates out the body from inside the body. This serves as protection for a diverse responsibilities, absorption, filtration, excretion, secretion, or sensory perception.

Causes and symptoms:

The most common cause of epithelioid mesothelioma is a place where fine particles and which are thrown into the air or by sawing or cutting. In epithelioid mesothelioma of the membrane lining the chest cavity, lungs, heart or abdominal cavity gets affected. In case of epithelioid mesothelioma patient survival time is about eight and a half months.

the rate at which a person is suffering as much as 50% to 70% of all cancer cells is the most common type. It was identified based on unique and organized cell structure which is tubular sample with a specific cell nucleus. Usually misdiagnoses diseases such cells in other cancers look very similar to the epithelioid cell adenocarcinoma is a type of cancer that is often confused with epithelioid mesothelioma.

is characterized by papillary or tubular growth, the most common subtype mestothelioma, there are many abnormal histological variants were found that include adenomatoid and deciduoid samples or tumor composed of small cells or mucin-positive cells, In addition to mesothelioma lepidic intrapulmonary growth.

Symptoms

Symptoms can occur after more than 40-50 years to be exposed to asbestos. This is most of the time mistaken for common asthma attacks, pneumonia or bronchitis because of symptoms of chest pain and breathlessness. Patients may have cough, weakness, fatigue, the inability to absorb nutrition causes weight loss. He also is a frequent gathering of fluid in the pleural space called the pleural effusion.The breath is caused when the tumor does not allow the lungs to expand and when spread on the results in severe chest pain.

Diagnosis

a thorough diagnosis is needed before any kind. As a latency period of this disease is the emergence of symptoms, early diagnosis becomes a difficult proposition. This is usually done only at an advanced stage leading to a survival rate of about 8-9 months.

To determine whether an individual has to undergo various diagnostic tests such as X-ray, MRI, CAT scan, Transbronchial biopsy, where the scope is passed through the trachea to the bronchi area of ​​the lung, thoracotomy where the chest open and check the ribs for any cancer, thoracoscopy, where video cameras are used to check the ribs or Centesis where pleural, peritoneal, or pericardial fluid is removed.

Friday, August 26, 2011

Lung Cancer Surgery Options



of lung cancer can be treated with various therapies that are often used in combination to provide the optimum outcome for the patient. Surgical resection is the process by which the tumor is surgically removed, it is usually recommended when the cancer has not metastasized (or spread) beyond the lungs to other parts of the body.

There are several options for performing resection, which may include minimally invasive surgery, or full operation. What techniques are used will depend on various factors, particularly the size and stage of cancer and whether the tumor can be accessed by a surgeon.

thoracotomy the surgeon performs an incision through the chest wall and median sternotomy performed by entering the chest through the breastbone. Both of these methods are usually employed in lung cancer surgery, but they do not involve significant patient discomfort and extended hospital stays with more periods of recovery.

Alternative surgical procedures include anterior limited thoracotomy (ALT), which involves a small incision to allow entry, again through the front of the chest. It should be noted that the incision is much smaller than a standard thoracotomy or median sternotomija.Alternativa the anterior axillary thoracotomy (AAT), which involves a small incision on the chest front, but in the armpits and in the end, there is a postero-lateral thoracotomy (PLT) , which involves an incision on the back or side of the patient's trunk.

Even with better surgical techniques, the patient will experience considerable pain, if the operation involves opening the chest (sometimes known among doctors as "cracking the chest ").

As a result of extended recovery time and patient discomfort, surgical techniques have been developed that do not involve full-blown operation -. These are the so-called minimally-invasive techniques

Video-assisted thoracoscopy (VAT) uses high-powered video cameras and hi-definition screen in combination with diagnostic scans such as CT or PET scans, to target tumors in the lung bolesnika.Rez should be much smaller and no need to open the chest, resulting in less discomfort for patients and greatly reduced the recovery period. Using the video display, the surgeon can resect tumors that were identified during the diagnosis and staging phases.

Some doctors caution the use of VAT, however, as the traditional thoracotomy can detect tumors and other cancers that metastasized were discovered in the initial scan and diagnosis. If you remain undetected cancer can return and the patient will become sick again and for that reason, the VAT is usually recommended for early stage (I and II), cancer, and not spread to other parts of the lungs and body.

It is normal for any surgical procedure to be followed by a phase of chemotherapy or radiation to ensure that the patient's cancer is completely removed or killed. Since treatment of income and in which phase the recommended treatment is determined by the type and stage of lung cancer the patient has.

Introduction to VATS Lobectomy Lung Surgery



There are more than 200,000 diagnosed cases of lung cancer (LC) each year in the United States. Although the incidence rate has been declining since 1991, the disease remains the leading cause of cancer-related deaths. When the condition is detected in stage 1 (ie, localized in the lungs), it can be treated successfully. By the time the cancerous cells have metastasized and spread to distant lymph nodes, it becomes harder to contain.

In the past, the disease is treated by thoracotomy (also known as open chest surgery). The patient's thoracic cavity access surgeon after a long incision is made in prsima.Prsne was cut and the ribs are spread to provide working space. Since the ribs have limited flexibility, the process sometimes resulted in fractures. To resolve this problem, thoracic surgeons began to remove parts of the patient's chest.

Today, minimally invasive techniques are often used to treat lung cancer. One of these techniques is a VATS lobectomy. This article will give an overview of the procedure and describe what to expect during recovery.

As the operation?

lobectomy is the surgical removal of the lobe (ie the portion of the lung). This is one of the most common procedure today for treatment of early LC. With VATS lobectomy, four incisions are made in the patient's chest. Three of the four sections are usually much less than one inča.Četvrti section can be measured to a few centimeters. No need to cut through the sternum and spread rebara.Cijeli procedure is carried out through these small incisions.

the surgeon will insert a thoracoscope, and several other surgical instruments through rezove.Thoracoscope is equipped with small lights and kamere.Fotoaparat transmits images back to the monitor uses the surgeon to see patients in the thoracic cavity.

The tumor is cut away from healthy tissue and extracted through one of the incisions. If the surgeon suspected cancerous cells have spread to nearby lymph nodes (ie the disease is in stage 2), some of them will be biopsied. This is done to confirm or disprove the spread of lung cancer to the lymph nodes.

Once the diseased tissue is removed, the surgeon will make sure that there are no signs of bleeding within the thoracic cavity. Four incisions are then closed and cleaned before the patient was transferred to a hospital recovery unit.

common questions about the work of

Before going through the screening process and go through the procedure, because patients often have many questions. For example, given the success rate for this type of lung cancer surgery and minimally invasive nature, some people wonder why they do not spend all bolnice.Odgovor is twofold. First, relatively few surgeons have mastered the techniques involved in VATS lobectomy. Second, some surgical centers lack the necessary equipment.

Another common area of confusion involves the patient's candidacy. Many people think this form of minimally invasive surgery of lung cancer can be performed on any person who is suffering from the disease. In reality, the procedure is generally reserved for those with stage 1 non-small cell LC.Tumor be measured at least three centimeters and remain localized in the lungs.

the recovery period after surgery is usually less than six tjedana.Pacijent will usually remain in hospital for two or three days after surgery. Then, he or she is released to complete their recovery at home. By the fourth week, most patients are able to return to their normal activity levels, although some require a full six weeks.

VATS lobectomy offers many advantages over traditional surgery, lung cancer was done through torakotomije.Vremena recovery is shorter, with less postoperative pain. In addition, the patient was able to return to normal life faster. If you are suffering from early stage lung cancer, ask your doctor whether you are a candidate for this approach.

Sunday, August 21, 2011

Mesothelioma Research Limitations and Computed Tomography



Another interesting study titled "Impact of drug light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma" Hans-Beat Ris, Hans Jörg Altermatt, Bernhard Nachbur, J. Charles M. Stewart, Qiang. Wang, Chang Kee Lim, Raymond Bonnett, Ulrich Althaus - International Journal of Cancer Volume 53, Number 1, p. 141-146, 2 January 1993 Here is an excerpt: "Summary - The influence of time interval (TI) between the drug and laser activation on the selectivity meta-tetrahydroxy-phenylchlorin (mTHPC)-mediated photodynamic therapy (PDT) for tumor tissue was evaluated in BALB / c nude mice bearing human malignant mesothelioma xenografts. the following IP administration of 0.3 mg / kg mTHPC, light dose of 10 J / cm2 and 0.1 W/cm2 was delivered at 650 nm in the tumor and the same size area of ​​the hind legs after the fourth I2, 24 and 36 hours, and 2.3, 4.5 and 6 days in groups of 6 animals (surface radiation ). Then, 72 hours after the delivery of light, depth of necrosis was measured in the tumor and the skin and underlying muscle hind legs. Photosensitized necrosis occurred in the normal tissue of the TI with 4 hr 3 days and tumor TI with I2 to 4 GB days. therapeutic ratio of mTHPC-PDT significantly varied with the time interval between the drug and the laser activated, and was the largest in the span of three days. mTHPC concentrations measured in 3 control unirradiated animals at all time points in normal tissues and tumor tissues, and it was found that same in both tissues. the tissue concentration of mTHPC was limited use in relation to the prediction of photosen-sitizing effects in tumor model ."

Another interesting study titled "Impact of drug light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma" Hans-Beat Ris, Hans Jörg Altermatt, Bernhard Nachbur, J. Charles M. Stewart, Qiang. Wang, Chang Kee Lim, Raymond Bonnett, Ulrich Althaus - International Journal of Cancer Volume 53, Number 1, p. 141-146, 2 January 1993 Here is an excerpt: "Summary - The influence of time interval (TI) between the drug and laser activation on the selectivity meta-tetrahydroxy-phenylchlorin (mTHPC)-mediated photodynamic therapy (PDT) for tumor tissue was evaluated in BALB / c nude mice bearing human malignant mesothelioma xenografts. the following IP administration of 0.3 mg / kg mTHPC, light dose of 10 J / cm2 and 0.1 W/cm2 was delivered at 650 nm in the tumor and the same size area of ​​the hind legs after the fourth I2, 24 and 36 hours, and 2.3, 4.5 and 6 days in groups of 6 animals (surface radiation ). Then, 72 hours after the delivery of light, depth of necrosis was measured in the tumor and the skin and underlying muscle hind legs. Photosensitized necrosis occurred in the normal tissue of the TI with 4 hr 3 days and tumor TI with I2 to 4 GB days. therapeutic ratio of mTHPC-PDT significantly varied with the time interval between the drug and the laser activated, and was the largest in the span of three days. mTHPC concentrations measured in 3 control unirradiated animals at all time points in normal tissues and tumor tissues, and it was found that same in both tissues. the tissue concentration of mTHPC was limited use in relation to the prediction of photosen-sitizing effects in tumor model ."

Another interesting study titled "Malignant mesothelioma of the pleura:. Clinical aspects and symptomatic treatment," Law MR, Hodson ME, Turner-Warwick M. Here is an excerpt: "Abstract - series of 140 patients with malignant pleural mesothelioma reported clinical presentation was postponed in the case without large effusion, but the tumor is extensive. the presentation, they showed thoracoscopy, thoracotomy, or computed tomography in all patients investigated. thoracoscopy was a useful diagnostic alternative to thoracotomy. with disease progression, mesothelial expansion was more important than distant metastases, which are usually too small and they rarely produce symptoms. skin tumor deposits in areas of previous invasive procedures are not causing pain or other clinical problems, and we believe that diagnostic and therapeutic procedures should not be withheld to avoid them. in the management recurrent pleural effusion, intrapleural bleomycin, preceded by desire, and after vacuuming, a useful alternative to surgery, pneumothorax, spontaneous or iatrogenic, it decortication Adequate pain relief is difficult .. radiation therapy and nerve block procedures were not effective and the drugs are often necessary. "

We all owe debt of gratitude to these fine researchers. If you find any of these statements interesting, please read the study in its entirety.

Saturday, August 20, 2011

Lung Cancer Diagnosis - How This Works



What makes the diagnosis of lung cancer? doctor evaluates a person's medical history, smoking history, exposure to environmental and work substances, a family history of cancer, as well as physical examination and chest X-ray to find the cause of symptoms. Other tests may be performed as needed.

the patient's history - if the doctor suspects lung cancer, they will: explore the medical history, perform a thorough physical examination, in order to further specialized medical tests. As part of its history, the doctor will ask you: If you smoke or have smoked before, your interest and

Place of work: if you were exposed to hazardous substances at work or radiation. Do you have a family history of lung cancer

Diagnosis of lung cancer
Screening helps find cancer at an early stage when cure is a series of tests before a person shows any symptoms. Early detection of abnormal tissue or cancer confirms the favorable treatment of the cancer completely unlike the detection of symptoms when the cancer could spread.

There are several ways to diagnose if someone is in the early stages of cancer pluća.Fizički examination and medical history: physical examination, checking general signs of health or disease, such as disease and unusual lumps, bumps and everything else that makes atipične.Liječnik will also get a history of personal health habits, any past illnesses and treatments given to those diseases.

Laboratory tests procedures for testing of tissue samples, blood, urine and other substances in tijelu.Testovi will also help in diagnosing the disease, as well as assist in planning, management and control of it.

sputum test : This may show evidence of cancer cells in the lungs. To ensure more accurate diagnosis with a single sputum collection, sputum is usually collected for three days.

optic bronchoscopy : an overview using a small flexible lighted tube to pass into the channel of the nose, then the corresponding bronchi (airways) to cancer. If cancer is detected, then a small piece of cancer was removed for biopsy examination so that the exact type of cancer can be determined and appropriate treatment given.

Percutaneous needle biopsy : This exam involves inserting a thin needle through the skin and chest into the tumor. This is a test for tumors that are near the surface of the lungs and is often used in conjunction with a CAT scan helps in guiding the needle into the tumor.

excision or surgical removal of the : This process can lead to further diagnosis of suspected tumor through a small incision in prsima.Mali thin video camera is inserted into the chest to assist in removing small block of lung tissue by mechanical surgical stapling device or laser with the clinical procedure.

Mediastinoscopy : This test helps to assess how extensive the tumor is looking into the middle of the chest through a small incision just below the collar line. Samples were taken from the lymph nodes in the middle of the chest (mediastinum). The chances for surgical treatment of lung cancer is automatically eliminated, if the cancer has spread to lymph nodes.

Mediastinotomy : Unlike mediastinoscopy, chest cavity is cut open the sternum (breastbone) and / or ribs allows the surgeon to reach and test more lymph nodes by removing samples of mediastinal lymph nodes. It is a complex test, a patient must undergo general anesthesia.

Thoracentesis . A sample of fluid around the lungs take a needle to check for cancer cells

thoracotomy . To test for malignancy in the chest must be opened to the procedure performed in the hospital as one of the major operations

thoracoscopy . Procedure using a thin, lighted tube connected to video cameras to monitor and review the space between the lungs and chest

bone marrow biopsy with a needle sample of bone is removed usually measuring about 1 / 16 inches across and 1 inch long. This is often taken back with the hip bone. A microscopic sample is checked for cancer cells. This procedure is performed primarily to diagnose small cell lung cancer.

blood test : complete blood test checks for the exact number of different cell types that show whether you have anemia or other related problems. Blood tests show chemical abnormalities in the organs and other body parts. Blood tests are repeated regularly, especially if someone is undergoing chemotherapy. Chemotherapy drugs affect blood-forming bone marrow cells, and sometimes cause a lot of problematic side effects. If the cancer has spread to his liver and bones, it could cause certain chemical abnormalities in the blood and exacerbate the problems already suffered a patient.

Other tests and procedures for the detection of lung cancer include:

Chest x-ray : Chest x-rays make up about half of all x-rays obtained at bolnicama.X-rays are usually done in order to get an evaluation of your lungs, heart and koš.Prsima pelvic x-ray test is the first doctor to look for any tumor or of the lungs. If it is normal there is probably a big no lung cancer, but if anything suspicious is detected, the doctor will order additional tests. Pneumonia, heart failure, emphysema, other medical conditions, and lung cancer can be located with the chest x-ray.

CT scan or Computed Tomography also known as CT or CAT scan : This equipment has been available over-sectional images of organs and tissues in tijelu.MAČKA scanning particularly useful for diagnosing the tumor as which is far more detail than conventional chest x-ray. It shows the different types of body tissues, including lung, heart, bone, soft tissue, muscle and blood vessels at the same time.

Modern CT scan images of breast from different angles using a method called spiral (or helical) CT. With the help of computers, processes images to create sectional images or "slices" of the area causing the concern. Images can then be printed or viewed on a monitor. To obtain a better picture after the first set of scans are taken intravenously, the radio-contrast agent was administered through a review of structures within tijela.Drugi set of pictures then it takes so that they can be examined together.

information on the size, shape and position of the tumor provide CT. This helps detect any enlarged lymph nodes, which could contain cancer that has spread from the lungs. When searching for early lung cancer and to ensure patients receive the treatment they need as quickly as possible, CT is much more sensitive than ordinary routine chest x-ray. In the search for tumors in the adrenal glands, brain and other internal organs most commonly affected lung cancer spread to CT is also useful.

Magnetic Resonance Imaging (MRI) : MRI use radio waves and strong magnets instead of x-zraka.Energije released from the radio waves is absorbed and re-released in a pattern shaped by the type tissues and disease under investigation.

pattern of radio waves is given by the tissues and organs are highly detailed images of body parts using a very sophisticated computer. It can also produce slices parallel to the length of his body as a CT scanner produces cross-section slices of the body.

positron emission tomography (PET) : This scan uses glucose, which is a form of sugar that contains a radioactive atom. Large quantities of radioactive sugar is absorbed into cancer cells, and a special camera is then able to detect radioactivity.

to find out if someone is suffering from early stage lung cancer PET scan is a very useful test. Often used to detect if the cancer has spread to lymph nodes. Fri scans are valuable in determining whether the shadows on chest x-ray is cancer or not. Fri scans are also helpful when the doctor thinks the cancer has spread, but not sure where the spread can be.

Given that PET scans to scan your whole body around the place of several different x-rays. Bone scan: a radioactive substance (usually technetium diphosphonate) is injected into venu.Radioaktivne substance accumulates in areas of bone is suspected of having cancer metastasis (spread). Because small amounts of radioactivity used to not cause any long-term consequences.

Bone scan results should be read in conjunction with the results of other tests performed, and other bone diseases can also cause an abnormal scan results. Bone scans are usually performed on patients with small cell lung cancer, and also in non-small cell lung cancer patients when other test results or symptoms suggest the cancer has spread to the bones - the diagnosis of lung cancer

Lung Cancer Diagnosis - How This Works



What makes the diagnosis of lung cancer? doctor evaluates a person's medical history, smoking history, exposure to environmental and work substances, a family history of cancer, as well as physical examination and chest X-ray to find the cause of symptoms. Other tests may be performed as needed.

the patient's history - if the doctor suspects lung cancer, they will: explore the medical history, perform a thorough physical examination, in order to further specialized medical tests. As part of its history, the doctor will ask you: If you smoke or have smoked before, your interest and

Place of work: if you were exposed to hazardous substances at work or radiation. Do you have a family history of lung cancer

Diagnosis of lung cancer
Screening helps find cancer at an early stage when cure is a series of tests before a person shows any symptoms. Early detection of abnormal tissue or cancer confirms the favorable treatment of the cancer completely unlike the detection of symptoms when the cancer could spread.

There are several ways to diagnose if someone is in the early stages of cancer pluća.Fizički examination and medical history: physical examination, checking general signs of health or disease, such as disease and unusual lumps, bumps and everything else that makes atipične.Liječnik will also get a history of personal health habits, any past illnesses and treatments given to those diseases.

Laboratory tests procedures for testing of tissue samples, blood, urine and other substances in tijelu.Testovi will also help in diagnosing the disease, as well as assist in planning, management and control of it.

sputum test : This may show evidence of cancer cells in the lungs. To ensure more accurate diagnosis with a single sputum collection, sputum is usually collected for three days.

optic bronchoscopy : an overview using a small flexible lighted tube to pass into the channel of the nose, then the corresponding bronchi (airways) to cancer. If cancer is detected, then a small piece of cancer was removed for biopsy examination so that the exact type of cancer can be determined and appropriate treatment given.

Percutaneous needle biopsy : This exam involves inserting a thin needle through the skin and chest into the tumor. This is a test for tumors that are near the surface of the lungs and is often used in conjunction with a CAT scan helps in guiding the needle into the tumor.

excision or surgical removal of the : This process can lead to further diagnosis of suspected tumor through a small incision in prsima.Mali thin video camera is inserted into the chest to assist in removing small block of lung tissue by mechanical surgical stapling device or laser with the clinical procedure.

Mediastinoscopy : This test helps to assess how extensive the tumor is looking into the middle of the chest through a small incision just below the collar line. Samples were taken from the lymph nodes in the middle of the chest (mediastinum). The chances for surgical treatment of lung cancer is automatically eliminated, if the cancer has spread to lymph nodes.

Mediastinotomy : Unlike mediastinoscopy, chest cavity is cut open the sternum (breastbone) and / or ribs allows the surgeon to reach and test more lymph nodes by removing samples of mediastinal lymph nodes. It is a complex test, a patient must undergo general anesthesia.

Thoracentesis . A sample of fluid around the lungs take a needle to check for cancer cells

thoracotomy . To test for malignancy in the chest must be opened to the procedure performed in the hospital as one of the major operations

thoracoscopy . Procedure using a thin, lighted tube connected to video cameras to monitor and review the space between the lungs and chest

bone marrow biopsy with a needle sample of bone is removed usually measuring about 1 / 16 inches across and 1 inch long. This is often taken back with the hip bone. A microscopic sample is checked for cancer cells. This procedure is performed primarily to diagnose small cell lung cancer.

blood test : complete blood test checks for the exact number of different cell types that show whether you have anemia or other related problems. Blood tests show chemical abnormalities in the organs and other body parts. Blood tests are repeated regularly, especially if someone is undergoing chemotherapy. Chemotherapy drugs affect blood-forming bone marrow cells, and sometimes cause a lot of problematic side effects. If the cancer has spread to his liver and bones, it could cause certain chemical abnormalities in the blood and exacerbate the problems already suffered a patient.

Other tests and procedures for the detection of lung cancer include:

Chest x-ray : Chest x-rays make up about half of all x-rays obtained at bolnicama.X-rays are usually done in order to get an evaluation of your lungs, heart and koš.Prsima pelvic x-ray test is the first doctor to look for any tumor or of the lungs. If it is normal there is probably a big no lung cancer, but if anything suspicious is detected, the doctor will order additional tests. Pneumonia, heart failure, emphysema, other medical conditions, and lung cancer can be located with the chest x-ray.

CT scan or Computed Tomography also known as CT or CAT scan : This equipment has been available over-sectional images of organs and tissues in tijelu.MAČKA scanning particularly useful for diagnosing the tumor as which is far more detail than conventional chest x-ray. It shows the different types of body tissues, including lung, heart, bone, soft tissue, muscle and blood vessels at the same time.

Modern CT scan images of breast from different angles using a method called spiral (or helical) CT. With the help of computers, processes images to create sectional images or "slices" of the area causing the concern. Images can then be printed or viewed on a monitor. To obtain a better picture after the first set of scans are taken intravenously, the radio-contrast agent was administered through a review of structures within tijela.Drugi set of pictures then it takes so that they can be examined together.

information on the size, shape and position of the tumor provide CT. This helps detect any enlarged lymph nodes, which could contain cancer that has spread from the lungs. When searching for early lung cancer and to ensure patients receive the treatment they need as quickly as possible, CT is much more sensitive than ordinary routine chest x-ray. In the search for tumors in the adrenal glands, brain and other internal organs most commonly affected lung cancer spread to CT is also useful.

Magnetic Resonance Imaging (MRI) : MRI use radio waves and strong magnets instead of x-zraka.Energije released from the radio waves is absorbed and re-released in a pattern shaped by the type tissues and disease under investigation.

pattern of radio waves is given by the tissues and organs are highly detailed images of body parts using a very sophisticated computer. It can also produce slices parallel to the length of his body as a CT scanner produces cross-section slices of the body.

positron emission tomography (PET) : This scan uses glucose, which is a form of sugar that contains a radioactive atom. Large quantities of radioactive sugar is absorbed into cancer cells, and a special camera is then able to detect radioactivity.

to find out if someone is suffering from early stage lung cancer PET scan is a very useful test. Often used to detect if the cancer has spread to lymph nodes. Fri scans are valuable in determining whether the shadows on chest x-ray is cancer or not. Fri scans are also helpful when the doctor thinks the cancer has spread, but not sure where the spread can be.

Given that PET scans to scan your whole body around the place of several different x-rays. Bone scan: a radioactive substance (usually technetium diphosphonate) is injected into venu.Radioaktivne substance accumulates in areas of bone is suspected of having cancer metastasis (spread). Because small amounts of radioactivity used to not cause any long-term consequences.

Bone scan results should be read in conjunction with the results of other tests performed, and other bone diseases can also cause an abnormal scan results. Bone scans are usually performed on patients with small cell lung cancer, and also in non-small cell lung cancer patients when other test results or symptoms suggest the cancer has spread to the bones - the diagnosis of lung cancer

Sunday, August 14, 2011

Mesothelioma and Pulmonary Decortication



Another interesting study titled "Pleurectomy for mesothelioma." Do Brancatisano RP, Joseph MG, McCaughan BC - Department of Surgery, Repatriation General Hospital Concord, NSW Med J Aust .. . 1st April 1991; 154 (7) :455-7, 460 Here is an excerpt: "Abstract - Objective: To evaluate the efficacy and safety of parietal pleurectomy in establishing a tissue diagnosis and control of pleural fluid accumulation in patients with pleural mesothelioma, and assess the success of this procedure caused mitigation DESIGN aND SETTING:. fifty consecutive patients with pleural mesothelioma who underwent thoracotomy for cardiac units in Concord and Royal Prince Alfred Hospital were reviewed retrospectively male:. female ratio was 04:01 and mean age was 63 years in only 11 of 50 patients had tissue diagnosis of mesothelioma was before the surgery INTERVENTIONS: .. the thoracotomy, subtotal parietal pleurectomy was performed in 45 of 50 patients in two patients. biopsy only was performed, and three patients were treated by chemical pleurodesis only as pleurectomy is not technically possible . pulmonary decortication was required in 28 patients to allow full expansion of the underlying lung for effective pleurodesis.

RESULTS: There was one postoperative smrt.Morbiditeta was 16%. Without a patient who died in the postoperative period, median survival was 16 months, ranging from three to 54 months, with 21% of patients surviving for more than two years. Only one patient developed a reaccumulation of pleural fluid.

Conclusion: Pleurectomy with decortication if necessary, and provide tissue diagnosis and effective control of pleural fluid accumulation and thus a great reduction in patients with pleural mesothelioma. We advocate early thoracotomy in these patients ."














Monday, August 8, 2011

Adenoviral Gene Transfer and Mesothelioma Cancer Cell Lines



Another interesting study called "adenovirus-mediated Bak gene transfer causes apoptosis in mesothelioma cell lines" by Abujiang Pataer, MD, PhD, W. Roy Smythe, Dr. Robert Yu, MS, Bingliang Fang, MD, PhD . sc, Tim McDonnell, MD, PhD, Jack A. Roth, Dr. Stephen G. Swisher, MD - from the Department of Thoracic Molecular Oncology, Department of Thoracic and cardiovascular surgery, and Institute of Molecular Pathology, University of Texas MD. Anderson Cancer Center, Houston, Texas - General Thoracic Surgery, J Thorac Cardiovasc Surg 2001; 121:0061-0067 Here is an excerpt: "Objective: Conventional treatment for mesothelioma is largely ineffective, therefore, evaluated the new approach. By adenoviral gene transfer of proapoptotic Bcl-2 family Bak in mesothelioma cancer cell lines, which are sensitive and resistant to adenoviral p53.

Methods: Binary adenoviral Bak (Ad / GT-Bak and Ad/GV16) and Laczi (Ad / GT-Laczi and Ad/GV16) vectors were used to convert from mesothelioma cell lines I-45 (p53-resistant ) and REN (p53-sensitive). Protein levels are determined by Western blotting. Apoptosis was assessed morphological changes, caspase-3 cleavage, and fluorescence-activated cell sorting analysis of subdiploid populations. Cell viability was determined by XTT assay. Statistical analysis was performed with analysis of variance and Student test.

Methods: Binary adenoviral Bak (Ad / GT-Bak and Ad/GV16) and Laczi (Ad / GT-Laczi and Ad/GV16) vectors were used to convert from mesothelioma cell lines I-45 (p53-resistant ) and REN (p53-sensitive). Protein levels are determined by Western blotting. Apoptosis was assessed morphological changes, caspase-3 cleavage, and fluorescence-activated cell sorting analysis of subdiploid populations. Cell viability was determined by XTT assay. Statistical analysis was performed with analysis of variance and Student test.

...

Methods: Binary adenoviral Bak (Ad / GT-Bak and Ad/GV16) and Laczi (Ad / GT-Laczi and Ad/GV16) vectors were used to convert from mesothelioma cell lines I-45 (p53-resistant ) and REN (p53-sensitive). Protein levels are determined by Western blotting. Apoptosis was assessed morphological changes, caspase-3 cleavage, and fluorescence-activated cell sorting analysis of subdiploid populations. Cell viability was determined by XTT assay. Statistical analysis was performed with analysis of variance and Student test.

...

Methods: Binary adenoviral Bak (Ad / GT-Bak and Ad/GV16) and Laczi (Ad / GT-Laczi and Ad/GV16) vectors were used to convert from mesothelioma cell lines I-45 (p53-resistant ) and REN (p53-sensitive). Protein levels are determined by Western blotting. Apoptosis was assessed morphological changes, caspase-3 cleavage, and fluorescence-activated cell sorting analysis of subdiploid populations. Cell viability was determined by XTT assay. Statistical analysis was performed with analysis of variance and Student test.

...

Adenoviral Gene Transfer and Mesothelioma Cancer Cell Lines



Another interesting study called "adenovirus-mediated Bak gene transfer causes apoptosis in mesothelioma cell lines" by Abujiang Pataer, MD, PhD, W. Roy Smythe, Dr. Robert Yu, MS, Bingliang Fang, MD, PhD . sc, Tim McDonnell, MD, PhD, Jack A. Roth, Dr. Stephen G. Swisher, MD - from the Department of Thoracic Molecular Oncology, Department of Thoracic and cardiovascular surgery, and Institute of Molecular Pathology, University of Texas MD. Anderson Cancer Center, Houston, Texas - General Thoracic Surgery, J Thorac Cardiovasc Surg 2001; 121:0061-0067 Here is an excerpt: "Objective: Conventional treatment for mesothelioma is largely ineffective, therefore, evaluated the new approach. By adenoviral gene transfer of proapoptotic Bcl-2 family Bak in mesothelioma cancer cell lines, which are sensitive and resistant to adenoviral p53.

Methods: Binary adenoviral Bak (Ad / GT-Bak and Ad/GV16) and Laczi (Ad / GT-Laczi and Ad/GV16) vectors were used to convert from mesothelioma cell lines I-45 (p53-resistant ) and REN (p53-sensitive). Protein levels are determined by Western blotting. Apoptosis was assessed morphological changes, caspase-3 cleavage, and fluorescence-activated cell sorting analysis of subdiploid populations. Cell viability was determined by XTT assay. Statistical analysis was performed with analysis of variance and Student test.

Results: High levels of Bak gene transfer were seen after coadministration Ad / GT-Bak and Ad/GV16 in both mesothelioma cell lines. Apoptosis is induced 24 hours after Bak but not Laczi gene transfer ([Bak: I-45, 36%, Ren, 25%] vs [Laczi: I-45, 1%, Ren, 3%], p <0 , 05]) in p53-sensitive (REN) and p53-resistant (I-45) cell lines. The cell viability was significantly reduced by 48 to 72 hours after Bak gene transfer compared with the control vector in both cell lines (72 hours: Bak I-45, 1.4% ± 1.0%, and Bak REN, 4.7% ± 1%, vs Lac-Z-45, 83% ± 3%, and Lac-Z REN, 100% ± 1%, P <0.05 ).


Conclusion: adenovirus-mediated overexpression of Bak gene causes apoptosis and decreased cell viability in p53-sensitive and p53-resistant mesothelioma cells. These data suggest that gene transfer of proapoptotic Bcl-2 family members may represent a novel strategy for gene therapy for treatment of mesothelioma.

Conclusion: adenovirus-mediated overexpression of Bak gene causes apoptosis and decreased cell viability in p53-sensitive and p53-resistant mesothelioma cells. These data suggest that gene transfer of proapoptotic Bcl-2 family members may represent a novel strategy for gene therapy for treatment of mesothelioma.

Lung Cancer Surgery - Life Can Get Much Better



undergoing lung cancer surgery

Cancers of the lung are divided into faze.Inscenacije system allows physicians to develop treatment plans and accurate prognoze.Položaj and grade of the tumor in the lung to determine if it is operable. When lung cancer surgery is an option, it is usually followed by additional treatments in both small cell and non small cell lung cancer (NSCLC and SCLC ).

thoracotomy

This procedure removes the malignant part of the lungs through an incision in the chest. There are three sub-classifications of this procedure. "Segmentectomy 'only removes the lung cancer tissue and a modest amount of surrounding healthy tissue. According to WebMD, the biggest return with segmentectomy, but it prevents a significant loss of lung function.

lobectomy removes the entire lobe of the lung. There are two on the left side and three on the right side, so that these bodies will continue. Surgeons remove the entire lobe to ensure the cancer is removed. In extreme cases, "pneumonectomy" performed to remove the entire lung. Lung function at reduced capacity after this operation.

The new technology allows surgeons to use VATS for the tumor. Barrels, or "video-assisted surgery thorascopic 'is less invasive then thoracotomy. This is useful for diagnosing cancer, taking tissue samples and when performing a segmentectomy. After surgery, patients will be assessed for lung function and general health before being released.

post-operative care

left thoracotomy chest aching for a long time and chest tube will be inserted into a drain built-up and blood was suctioned tekućine.Fluid the machine and drained to the container. Chest tubes were removed when drainage stops. Although the tubes are often removed within a week, it takes several weeks to recover from this operation.

Respiratory therapists work with post-op patients to improve lung function. The methods include deep breathing exercises in combination with medication to open airways. Extra Care May be required for lobectomy. Studies have shown that surgery increases survival, but complications such as bleeding or pain persisting event.

before surgery is recommended as an option, the patient's pulmonary function and overall heart health are assessed.

Sunday, August 7, 2011

Lung Cancer Surgery - Life Can Get Much Better


This procedure removes the malignant part of the lungs through an incision in the chest. There are three sub-classifications of this procedure. "Segmentectomy 'only removes the lung cancer tissue and a modest amount of surrounding healthy tissue. According to WebMD, the biggest return with segmentectomy, but it prevents a significant loss of lung function.

lobectomy removes the entire lobe of the lung. There are two on the left side and three on the right side, so that these bodies will continue. Surgeons remove the entire lobe to ensure the cancer is removed. In extreme cases, "pneumonectomy" performed to remove the entire lung. Lung function at reduced capacity after this operation.

The new technology allows surgeons to use VATS for the tumor. Barrels, or "video-assisted surgery thorascopic 'is less invasive then thoracotomy. This is useful for diagnosing cancer, taking tissue samples and when performing a segmentectomy. After surgery, patients will be assessed for lung function and general health before being released.

post-operative care
left thoracotomy chest aching for a long time and chest tube will be inserted into a drain built-up and blood was suctioned tekućine.Fluid the machine and drained to the container. Chest tubes were removed when drainage stops. Although the tubes are often removed within a week, it takes several weeks to recover from this operation.

Respiratory therapists work with post-op patients to improve lung function. The methods include deep breathing exercises in combination with medication to open airways. Extra Care May be required for lobectomy. Studies have shown that surgery increases survival, but complications such as bleeding or pain persisting event.

before surgery is recommended as an option, the patient's pulmonary function and overall heart health are assessed.

Lung Cancer Surgery - Life Can Get Much Better


undergoing lung cancer surgery
Cancers of the lung are divided into faze.Inscenacije system allows physicians to develop treatment plans and accurate prognoze.Položaj and grade of the tumor in the lung to determine if it is operable. When lung cancer surgery is an option, it is usually followed by additional treatments in both small cell and non small cell lung cancer (NSCLC and SCLC ).

thoracotomy
This procedure removes the malignant part of the lungs through an incision in the chest. There are three sub-classifications of this procedure. "Segmentectomy 'only removes the lung cancer tissue and a modest amount of surrounding healthy tissue. According to WebMD, the biggest return with segmentectomy, but it prevents a significant loss of lung function.
lobectomy removes the entire lobe of the lung. There are two on the left side and three on the right side, so that these bodies will continue. Surgeons remove the entire lobe to ensure the cancer is removed. In extreme cases, "pneumonectomy" performed to remove the entire lung. Lung function at reduced capacity after this operation.
The new technology allows surgeons to use VATS for the tumor. Barrels, or "video-assisted surgery thorascopic 'is less invasive then thoracotomy. This is useful for diagnosing cancer, taking tissue samples and when performing a segmentectomy. After surgery, patients will be assessed for lung function and general health before being released.

post-operative care
left thoracotomy chest aching for a long time and chest tube will be inserted into a drain built-up and blood was suctioned tekućine.Fluid the machine and drained to the container. Chest tubes were removed when drainage stops. Although the tubes are often removed within a week, it takes several weeks to recover from this operation.

Respiratory therapists work with post-op patients to improve lung function. The methods include deep breathing exercises in combination with medication to open airways. Extra Care May be required for lobectomy. Studies have shown that surgery increases survival, but complications such as bleeding or pain persisting event.
before surgery is recommended as an option, the patient's pulmonary function and overall heart health are assessed.

Saturday, August 6, 2011

What is a VATS Lobectomy?

According to the American Cancer Society, nearly 220,000 new cases of lung cancer (LC) was diagnosed in 2009. Nearly 160,000 people have died from the disease during the same year. It is the leading cause of cancer related death in both sexes. Surgical approach to resolving the situation included wedge resections, lobectomies and pneumonectomies.Svrha this article is to explore ways in which lobectomies are performed. It is an operation during which a lobe of your lung is excised.

The operation has evolved considerably over the past few decades. It used to be an invasive procedure that is accompanied by a high level of postoperative pain and long recovery period. Today, the approach taken an increasing number of surgeons provides much better result.

In the following, we will once again traditional lobectomies and explain how to perform. While minimally invasive techniques are better, some circumstances make this approach inappropriate. We will also describe the basics of VATS lobectomy and explain some of the tests involved in determining whether you are eligible. Finally, you'll learn what to expect while recovering in hospital and at home.

The traditional explanation lobectomy

traditional lobectomies performed through a thoracotomy, open access to prsima.Dugi incision was made by the surgeon in the side of the chest between the ribs. The whole operation was completed through this one rez.Pacijenta ribs are spread apart with a retractor to provide the surgical team enough room to access the lung. Then, the necessary instruments are inserted into the chest cavity in order to clarify and remove the diseased lobe.

because it is invasive thoracotomy, the patient will experience a significant amount of pain after surgery. In addition, a few weeks needed to recover to the extent that the continuation of normal activities.

Fundamentals of VATS lobectomy

Lobectomies can also be performed using video-assisted thoracic surgery (VATS). It is a minimally invasive alternative to thoracotomy. Instead of making a long incision in the patient's chest and spreading the ribs, the surgeon makes several small incisions on both sides of the chest. Most are less than one inch.

thin instrument called a thoracoscope is inserted through one of the incisions. It is a little light and camera attached to the top. As a surgeon takes thoracoscope into the chest cavity, the camera sends images back to the video monitor. These images provide the surgeon with a clearer view of the lungs and surrounding structures than can be achieved through a thoracotomy.

Additional instruments are inserted through other small incisions to reduce and extract the diseased lobe.

determine whether you are a candidate

Patients who have lung cancer that has progressed into phase II May not be suitable candidates for VATS lobektomije.Postupak is usually reserved for those with tumors smaller than 3 cm. Moreover, if cancer cells have metastasized beyond the lung, video-assisted thoracic surgery generally is excluded as an option. In such cases, as well as those in which tumors are large, traditional thoracotomy is often recommended.

is recovering in hospital and at home

after VATS lung cancer surgery, you can expect to remain in hospital for four days (although some patients are published in just two days). During this time, nurses and surgical team will work closely with you to help you recover. Once your doctor is convinced that your body is tolerated procedure and is recovering well, you will be released from the hospital.

before returning home, your doctor will give instructions on how to keep the place clean cut, the types of activities to avoid, and recommended diet. Most patients are able to return to their jobs (unless their work requires strenuous activity) within a few weeks. By the sixth week, you May be able to continue with normal routines, including strenuous activities.

VATS lobectomies are a popular approach to dealing with early stage lung cancer. Talk with your doctor to determine whether this minimally invasive technique is available and fits your circumstances.


Friday, August 5, 2011

Mesothelioma Research Limitations and Computed Tomography


Another interesting study titled "Impact of drug light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma" Hans-Beat Ris, Hans Jörg Altermatt, Bernhard Nachbur, J. Charles M. Stewart, Qiang. Wang, Chang Kee Lim, Raymond Bonnett, Ulrich Althaus - International Journal of Cancer Volume 53, Number 1, p. 141-146, 2 January 1993 Here is an excerpt: "Summary - The influence of time interval (TI) between the drug and laser activation on the selectivity meta-tetrahydroxy-phenylchlorin (mTHPC)-mediated photodynamic therapy (PDT) for tumor tissue was evaluated in BALB / c nude mice bearing human malignant mesothelioma xenografts. the following IP administration of 0.3 mg / kg mTHPC, light dose of 10 J / cm2 and 0.1 W/cm2 was delivered at 650 nm in the tumor and the same size area of ​​the hind legs after the fourth I2, 24 and 36 hours, and 2.3, 4.5 and 6 days in groups of 6 animals (surface radiation ). Then, 72 hours after the delivery of light, depth of necrosis was measured in the tumor and the skin and underlying muscle hind legs. Photosensitized necrosis occurred in the normal tissue of the TI with 4 hr 3 days and tumor TI with I2 to 4 GB days. therapeutic ratio of mTHPC-PDT significantly varied with the time interval between the drug and the laser activated, and was the largest in the span of three days. mTHPC concentrations measured in 3 control unirradiated animals at all time points in normal tissues and tumor tissues, and it was found that same in both tissues. the tissue concentration of mTHPC was limited use in relation to the prediction of photosen-sitizing effects in tumor model ."

Another interesting study titled "Impact of drug light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma" Hans-Beat Ris, Hans Jörg Altermatt, Bernhard Nachbur, J. Charles M. Stewart, Qiang. Wang, Chang Kee Lim, Raymond Bonnett, Ulrich Althaus - International Journal of Cancer Volume 53, Number 1, p. 141-146, 2 January 1993 Here is an excerpt: "Summary - The influence of time interval (TI) between the drug and laser activation on the selectivity meta-tetrahydroxy-phenylchlorin (mTHPC)-mediated photodynamic therapy (PDT) for tumor tissue was evaluated in BALB / c nude mice bearing human malignant mesothelioma xenografts. the following IP administration of 0.3 mg / kg mTHPC, light dose of 10 J / cm2 and 0.1 W/cm2 was delivered at 650 nm in the tumor and the same size area of ​​the hind legs after the fourth I2, 24 and 36 hours, and 2.3, 4.5 and 6 days in groups of 6 animals (surface radiation ). Then, 72 hours after the delivery of light, depth of necrosis was measured in the tumor and the skin and underlying muscle hind legs. Photosensitized necrosis occurred in the normal tissue of the TI with 4 hr 3 days and tumor TI with I2 to 4 GB days. therapeutic ratio of mTHPC-PDT significantly varied with the time interval between the drug and the laser activated, and was the largest in the span of three days. mTHPC concentrations measured in 3 control unirradiated animals at all time points in normal tissues and tumor tissues, and it was found that same in both tissues. the tissue concentration of mTHPC was limited use in relation to the prediction of photosen-sitizing effects in tumor model ."

Another interesting study titled "Malignant mesothelioma of the pleura:. Clinical aspects and symptomatic treatment," Law MR, Hodson ME, Turner-Warwick M. Here is an excerpt: "Abstract - series of 140 patients with malignant pleural mesothelioma reported clinical presentation was postponed in the case without large effusion, but the tumor is extensive. the presentation, they showed thoracoscopy, thoracotomy, or computed tomography in all patients investigated. thoracoscopy was a useful diagnostic alternative to thoracotomy. with disease progression, mesothelial expansion was more important than distant metastases, which are usually too small and they rarely produce symptoms. skin tumor deposits in areas of previous invasive procedures are not causing pain or other clinical problems, and we believe that diagnostic and therapeutic procedures should not be withheld to avoid them. in the management recurrent pleural effusion, intrapleural bleomycin, preceded by desire, and after vacuuming, a useful alternative to surgery, pneumothorax, spontaneous or iatrogenic, it decortication Adequate pain relief is difficult .. radiation therapy and nerve block procedures were not effective and the drugs are often necessary. "

We all owe debt of gratitude to these fine researchers. If you find any of these statements interesting, please read the study in its entirety.

Thursday, August 4, 2011

Traditional Versus Minimally Invasive Lung Cancer Surgery


There are a number of reasons, the operation is performed on pluća.Najčešći reason including cancer. If a mass is identified in lung tissue, the surgical team will be assigned to remove it. There are several approaches that can be taken, depending on where a mass, as well as its size. Surgery can also perform the fix, or collapsed lung to drain fluid that accumulates in the vicinity.

Today, minimally invasive techniques are used to reduce the likelihood of complications and provide a shorter recovery period for the patient. In this article, we will provide an overview of the differences between traditional thoracotomy and minimally invasive surgery of lung cancer. While the former is still done in some circumstances, the latter is becoming increasingly common.

The types of surgical procedures

First, it is worth considering the different operations performed on the lungs. As noted, most surgical procedures are done to cure lung cancer (LC). If this mass is small and can be found only in a small piece of tissue, a wedge resection is performed to remove that part.

In cases where cancer cells are detected within a larger piece of tissue, lobectomy can be done. This is a procedure in which an entire lobe is removed. If you need to remove two adjacent lobes, the procedure is called bilobectomy.

When the diseased cells have spread throughout the lung, the surgeon will perform a pneumonectomy to remove the entire organ. His absence will reduce the patient's quality of life, but the patient can live with only one lung.

Minimally invasive approach

Traditionally, lung cancer surgery was performed through an open chest surgery (ie thoracotomy). Long incision was made in patients by between rebara.Kirurg then uses a retractor to spread the ribs of the patient in order to provide enough space to work. Along with the ribs spread apart, the surgeon access to the site and removed the tumor.

Thoracoscopy can achieve the same results without having to make a long incision and spreading the ribs. Instead, the surgeon will make a few minor rezova.Tanka, tubular instrument called a thoracoscope is equipped with a video camera and inserted through a small incision. As a surgeon takes thoracoscope to the affected tissue, video camera transmits images of the thorax back to the surgical team.

Once the site is identified, other instruments are inserted and guided patients tkiva.Dio contains cancerous cells is cut away and removed.

Differences between traditional and minimally invasive surgery

Since it is so invasive thoracotomy, patients are exposed to several potential complications. This may include respiratory failure, internal bleeding, pneumonia, and air leaks. In addition, the patient is forced to cope with intense postoperative pain during recovery.

With minimally invasive surgery of lung cancer, the potential for complications is significantly reduced. There is far less postoperative pain and recovery period is shortened. It is not uncommon for patients to be released from hospital after two or three days after surgery (compared to up to ten days after thoracotomy).

What to expect after surgery

After the surgery of lung cancer (assuming that the minimally invasive technique), you will experience some degree of tenderness near rezova.Bol will eventually subside. Within a few days, you will be released to complete their recovery at home. Your doctor will prescribe pain medication to minimize discomfort behind. Once you no longer need this medication, you will be able to resume their normal activities. Most patients find that they can return to their normal routine after four or five weeks.

Not everyone is a candidate for minimally invasive surgery of lung cancer. Your doctor will want to perform several tests to verify whether this treatment is appropriate with respect to the performance of the disease and your condition.

Traditional Versus Minimally Invasive Lung Cancer Surgery

There are a number of reasons, the operation is performed on pluća.Najčešći reason including cancer. If a mass is identified in lung tissue, the surgical team will be assigned to remove it. There are several approaches that can be taken, depending on where a mass, as well as its size. Surgery can also perform the fix, or collapsed lung to drain fluid that accumulates in the vicinity.

Today, minimally invasive techniques are used to reduce the likelihood of complications and provide a shorter recovery period for the patient. In this article, we will provide an overview of the differences between traditional thoracotomy and minimally invasive surgery of lung cancer. While the former is still done in some circumstances, the latter is becoming increasingly common.

The types of surgical procedures

First, it is worth considering the different operations performed on the lungs. As noted, most surgical procedures are done to cure lung cancer (LC). If this mass is small and can be found only in a small piece of tissue, a wedge resection is performed to remove that part.

In cases where cancer cells are detected within a larger piece of tissue, lobectomy can be done. This is a procedure in which an entire lobe is removed. If you need to remove two adjacent lobes, the procedure is called bilobectomy.

When the diseased cells have spread throughout the lung, the surgeon will perform a pneumonectomy to remove the entire organ. His absence will reduce the patient's quality of life, but the patient can live with only one lung.

Minimally invasive approach

Traditionally, lung cancer surgery was performed through an open chest surgery (ie thoracotomy). Long incision was made in patients by between rebara.Kirurg then uses a retractor to spread the ribs of the patient in order to provide enough space to work. Along with the ribs spread apart, the surgeon access to the site and removed the tumor.

Thoracoscopy can achieve the same results without having to make a long incision and spreading the ribs. Instead, the surgeon will make a few minor rezova.Tanka, tubular instrument called a thoracoscope is equipped with a video camera and inserted through a small incision. As a surgeon takes thoracoscope to the affected tissue, video camera transmits images of the thorax back to the surgical team.

Once the site is identified, other instruments are inserted and guided patients tkiva.Dio contains cancerous cells is cut away and removed.

Differences between traditional and minimally invasive surgery

Since it is so invasive thoracotomy, patients are exposed to several potential complications. This may include respiratory failure, internal bleeding, pneumonia, and air leaks. In addition, the patient is forced to cope with intense postoperative pain during recovery.

With minimally invasive surgery of lung cancer, the potential for complications is significantly reduced. There is far less postoperative pain and recovery period is shortened. It is not uncommon for patients to be released from hospital after two or three days after surgery (compared to up to ten days after thoracotomy).

What to expect after surgery

After the surgery of lung cancer (assuming that the minimally invasive technique), you will experience some degree of tenderness near rezova.Bol will eventually subside. Within a few days, you will be released to complete their recovery at home. Your doctor will prescribe pain medication to minimize discomfort behind. Once you no longer need this medication, you will be able to resume their normal activities. Most patients find that they can return to their normal routine after four or five weeks.

Not everyone is a candidate for minimally invasive surgery of lung cancer. Your doctor will want to perform several tests to verify whether this treatment is appropriate with respect to the performance of the disease and your condition.

Mesothelioma Research Limitations and Computed Tomography

Another interesting study titled "Impact of drug light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma" Hans-Beat Ris, Hans Jörg Altermatt, Bernhard Nachbur, J. Charles M. Stewart, Qiang. Wang, Chang Kee Lim, Raymond Bonnett, Ulrich Althaus - International Journal of Cancer Volume 53, Number 1, p. 141-146, 2 January 1993 Here is an excerpt: "Summary - The influence of time interval (TI) between the drug and laser activation on the selectivity meta-tetrahydroxy-phenylchlorin (mTHPC)-mediated photodynamic therapy (PDT) for tumor tissue was evaluated in BALB / c nude mice bearing human malignant mesothelioma xenografts. the following IP administration of 0.3 mg / kg mTHPC, light dose of 10 J / cm2 and 0.1 W/cm2 was delivered at 650 nm in the tumor and the same size area of ​​the hind legs after the fourth I2, 24 and 36 hours, and 2.3, 4.5 and 6 days in groups of 6 animals (surface radiation ). Then, 72 hours after the delivery of light, depth of necrosis was measured in the tumor and the skin and underlying muscle hind legs. Photosensitized necrosis occurred in the normal tissue of the TI with 4 hr 3 days and tumor TI with I2 to 4 GB days. therapeutic ratio of mTHPC-PDT significantly varied with the time interval between the drug and the laser activated, and was the largest in the span of three days. mTHPC concentrations measured in 3 control unirradiated animals at all time points in normal tissues and tumor tissues, and it was found that same in both tissues. the tissue concentration of mTHPC was limited use in relation to the prediction of photosen-sitizing effects in tumor model ."

Another interesting study titled "Impact of drug light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma" Hans-Beat Ris, Hans Jörg Altermatt, Bernhard Nachbur, J. Charles M. Stewart, Qiang. Wang, Chang Kee Lim, Raymond Bonnett, Ulrich Althaus - International Journal of Cancer Volume 53, Number 1, p. 141-146, 2 January 1993 Here is an excerpt: "Summary - The influence of time interval (TI) between the drug and laser activation on the selectivity meta-tetrahydroxy-phenylchlorin (mTHPC)-mediated photodynamic therapy (PDT) for tumor tissue was evaluated in BALB / c nude mice bearing human malignant mesothelioma xenografts. the following IP administration of 0.3 mg / kg mTHPC, light dose of 10 J / cm2 and 0.1 W/cm2 was delivered at 650 nm in the tumor and the same size area of ​​the hind legs after the fourth I2, 24 and 36 hours, and 2.3, 4.5 and 6 days in groups of 6 animals (surface radiation ). Then, 72 hours after the delivery of light, depth of necrosis was measured in the tumor and the skin and underlying muscle hind legs. Photosensitized necrosis occurred in the normal tissue of the TI with 4 hr 3 days and tumor TI with I2 to 4 GB days. therapeutic ratio of mTHPC-PDT significantly varied with the time interval between the drug and the laser activated, and was the largest in the span of three days. mTHPC concentrations measured in 3 control unirradiated animals at all time points in normal tissues and tumor tissues, and it was found that same in both tissues. the tissue concentration of mTHPC was limited use in relation to the prediction of photosen-sitizing effects in tumor model ."

Another interesting study titled "Malignant mesothelioma of the pleura:. Clinical aspects and symptomatic treatment," Law MR, Hodson ME, Turner-Warwick M. Here is an excerpt: "Abstract - series of 140 patients with malignant pleural mesothelioma reported clinical presentation was postponed in the case without large effusion, but the tumor is extensive. the presentation, they showed thoracoscopy, thoracotomy, or computed tomography in all patients investigated. thoracoscopy was a useful diagnostic alternative to thoracotomy. with disease progression, mesothelial expansion was more important than distant metastases, which are usually too small and they rarely produce symptoms. skin tumor deposits in areas of previous invasive procedures are not causing pain or other clinical problems, and we believe that diagnostic and therapeutic procedures should not be withheld to avoid them. in the management recurrent pleural effusion, intrapleural bleomycin, preceded by desire, and after vacuuming, a useful alternative to surgery, pneumothorax, spontaneous or iatrogenic, it decortication Adequate pain relief is difficult .. radiation therapy and nerve block procedures were not effective and the drugs are often necessary. "

We all owe debt of gratitude to these fine researchers. If you find any of these statements interesting, please read the study in its entirety.