Another interesting study entitled "Pleural mesothelioma of connective tissue type, localized fibrous tumor of the pleura, and reactive hyperplasia submesothelial immunohistochemical comparison." Moutaiz by Al-Izzi, Nicola P. Thurlow, Professor Bryan Corrin -. Journal of Pathology, Volume 158, Issue 1, pages 41-44, May 1989 Here is an excerpt: "Abstract - Ten diffuse pleural mesotheliomas connective tissue type were compared with 14 examples of pleural granulation tissue and 7 localized fibrous tumors of the pleura, using immunohistochemistry to identify cytokeralins oflow and high molecular weight and vimentin. low-molecular-weight cytokeratin and vimentin are both delected in 8 of 10 mesotheliomas and 12 of 14 reactive iesions. cylokeratin high molecular weight is rarely detected or lesions. seven of localized fibrous tumors of the pleura are all positive and negative for virnentin for cytokeratins. These results support the origin of connective tissue type mesotheliomas multipotential submesothelial spindle cells and localized fibrous tumors of the pleura from any conventional fibroblasts or resting submesothelial stem cells. cytokeratin antibodies to help distinguish these two neoplasms, but does not provide help in difficult diagnostic problem of distinguishing mesotheliomas of the connective tissue type of pleural reaction is characterized by abundant granulation tissue ."
Another interesting study titled, "Final analysis of multi-center, double-blind, placebo-controlled, randomized phase II trial of gemcitabine / cisplatin (GC) plus bevacizumab (B) or placebo (P) in patients (pts ) with malignant mesothelioma (MM) "-
Another interesting study titled, "Final analysis of multi-center, double-blind, placebo-controlled, randomized phase II trial of gemcitabine / cisplatin (GC) plus bevacizumab (B) or placebo (P) in patients (pts ) with malignant mesothelioma (MM) "-
0 comments:
Post a Comment